Kindly help how can I get CFR11 settings enabled in my DocuSign Sand Box or Demo Account?
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For developer accounts, DocuSign Customer Service handles that for you:
Remember to include your developer account ID with your request to enable a feature on your account.
To have a feature enabled, open a case with customer support. Best practice: use the Support Portal to login with your production (not developer) DocuSign credentials.
Or use the general web form on the contact support page. Use the DocuSign API Integration Support option at the bottom of the page.

Larry K
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1As an additional note, getting the 21 CFR Part 11 module enabled in Production does require a conversation with Sales. If you already have a point of contact on that side, you can also work with them to get your Sandbox account enabled for 21 CFR Part 11 – Drew Jan 19 '22 at 20:03